Assessing Progress in Reducing the At-Risk Population after 13 Years of the Global Programme to Eliminate Lymphatic Filariasis
Identifieur interne : 002D34 ( Main/Exploration ); précédent : 002D33; suivant : 002D35Assessing Progress in Reducing the At-Risk Population after 13 Years of the Global Programme to Eliminate Lymphatic Filariasis
Auteurs : Pamela J. Hooper [États-Unis] ; Brian K. Chu [États-Unis] ; Alexei Mikhailov [Suisse] ; Eric A. Ottesen [États-Unis] ; Mark Bradley [Royaume-Uni]Source :
- PLoS Neglected Tropical Diseases [ 1935-2727 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
- traitement médicamenteux : Filariose lymphatique.
- usage thérapeutique : Filaricides.
- épidémiologie : Filariose lymphatique.
- Filariose lymphatique, Humains, Modèles biologiques, Modèles statistiques, Santé mondiale, Santé publique, Évaluation des risques.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Filaricides.
- drug therapy : Elephantiasis, Filarial.
- epidemiology : Elephantiasis, Filarial.
- prevention & control : Elephantiasis, Filarial.
- Global Health, Humans, Models, Biological, Models, Statistical, Public Health, Risk Assessment.
Abstract
In 1997, the World Health Assembly adopted Resolution 50.29, committing to the elimination of lymphatic filariasis (LF) as a public health problem, subsequently targeted for 2020. The initial estimates were that 1.2 billion people were at-risk for LF infection globally. Now, 13 years after the Global Programme to Eliminate Lymphatic Filariasis (GPELF) began implementing mass drug administration (MDA) against LF in 2000—during which over 4.4 billion treatments have been distributed in 56 endemic countries—it is most appropriate to estimate the impact that the MDA has had on reducing the population at risk of LF.
To assess GPELF progress in reducing the population at-risk for LF, we developed a model based on defining reductions in risk of infection among cohorts of treated populations following each round of MDA. The model estimates that the number of people currently at risk of infection decreased by 46% to 789 million through 2012.
Important progress has been made in the global efforts to eliminate LF, but significant scale-up is required over the next 8 years to reach the 2020 elimination goal.
Url:
DOI: 10.1371/journal.pntd.0003333
PubMed: 25411843
PubMed Central: 4239000
Affiliations:
- Royaume-Uni, Suisse, États-Unis
- Angleterre, District de Columbia, Grand Londres, Géorgie (États-Unis)
- Londres, Washington (district de Columbia)
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Le document en format XML
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<term>Santé publique</term>
<term>Évaluation des risques</term>
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<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>In 1997, the World Health Assembly adopted Resolution 50.29, committing to the elimination of lymphatic filariasis (LF) as a public health problem, subsequently targeted for 2020. The initial estimates were that 1.2 billion people were at-risk for LF infection globally. Now, 13 years after the Global Programme to Eliminate Lymphatic Filariasis (GPELF) began implementing mass drug administration (MDA) against LF in 2000—during which over 4.4 billion treatments have been distributed in 56 endemic countries—it is most appropriate to estimate the impact that the MDA has had on reducing the population at risk of LF.</p>
</sec>
<sec><title>Methodology/Principal Findings</title>
<p>To assess GPELF progress in reducing the population at-risk for LF, we developed a model based on defining reductions in risk of infection among cohorts of treated populations following each round of MDA. The model estimates that the number of people currently at risk of infection decreased by 46% to 789 million through 2012.</p>
</sec>
<sec><title>Conclusions/Significance</title>
<p>Important progress has been made in the global efforts to eliminate LF, but significant scale-up is required over the next 8 years to reach the 2020 elimination goal.</p>
</sec>
</div>
</front>
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<country name="Suisse"><noRegion><name sortKey="Mikhailov, Alexei" sort="Mikhailov, Alexei" uniqKey="Mikhailov A" first="Alexei" last="Mikhailov">Alexei Mikhailov</name>
</noRegion>
</country>
<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Bradley, Mark" sort="Bradley, Mark" uniqKey="Bradley M" first="Mark" last="Bradley">Mark Bradley</name>
</region>
</country>
</tree>
</affiliations>
</record>
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